Clusters of polygonal cells are present. No distinct architectural features are present.
Cellularity varies, with some foci of closely situated polygonal cells present. Nuclear atypia is not signficant.
Cells are surrounded by some hyalinized stroma, and show pale to slightly pink cytoplasm.
Juxtaglomerular cell tumor (JCT), also called juxtaglomerular cell apparatus tumor or reninoma, is a rare benign renal neoplasm first described in 1967.
Typically occur in relatively young patients (avg age 26). Patients may present with hypertension, hyperaldosteronism, and hypokalemia, due to renin secretion by the tumor. Other symptoms may include headache, polyuria, nocturia, dizziness and vomiting.
Partial nephrectomy is recommended. as the tumor is benign and usually small, and no recurrence or metastasis occurred except one metastatic patient.