Haphazardly distributed glands are irregularly dispersed within a fibroblastic stroma. There is no evidence of a lobular configuration. A few normal glands are seen along the periphery.
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Another case is seen here. Small angulated glands are seen dissecting through the stroma.
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The entire tumor showed well formed glands, which often have a teardrop or angular outline. Single cells infiltrating the stroma are lacking. Some residual fat is seen admixed with the infiltration.
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Aspiration of the tumor showed numerous well formed glandular structures and mild atypia. The background lacks necrosis and debris.
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Keratin 7 staining highlights the scattered single cells and the glands.
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Due to the consideration of papillary mesothelial hyperplasia, ER was done which is strongly positive.
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Compared with infiltrating ductal carcinoma, tubular carcinoma is associated with more favorable outcome after breast conservation therapy, suggesting the appropriateness of a conservative approach for this subtype. (Lui). Approximately 8% are associated with nodal disease, and these instances are associated with larger tumor size (Javid) w
Lui GF et al. Clinical-Pathologic Features and Long-Term Outcomes of Tubular Carcinoma of the Breast Compared with Invasive Ductal Carcinoma Treated with Breast Conservation Therapy. Int J Radiat Oncol Biol Phys. April, 2009
Javid SH. Tubular carcinoma of the breast: results of a large contemporary series. Am J Surg. 2009 ;197(5):674-7.